P300 latency as an indicator of severity in major depressive disorder

P300 latency as an indicator of severity in major depressive disorder Tripathi SM, Mishra N, Tripathi RK, Gurnani K C - Ind Psychiatry J

Background: Depression is the most common mental health problem across all the age groups. Still diagnostic techniques and laboratory tests are awaited to confirm it. Some studies focus on P300 latency to aid in the diagnosis of depression. Hence, this study was conducted to know whether P300 latency is an indicator of major depressive disorder (MDD). Methods: This study was conducted both on patients admitted in the hospital and those attending outdoor clinic giving written informed consent and fulfilling inclusion/exclusion criteria from the Department of Psychiatry, S.N. Medical College and Hospital, Agra. The sample consisted of 30 consecutive patients suffering from MDD as per the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and 30 subjects as normal control. Sociodemographic and clinical history proforma, Hamilton Rating Scale for Depression (Ham-D), and P300 were administered on all 60 subjects. Data were analyzed using mean, standard deviation, and t-test. Results: Significant difference (P < 0.0001) has been found in HAM-D mean scores of depressed and nondepressed control group subjects. The mean score of depressed group was significantly high (18.066) compared to nondepressed control group (4.833). Significant difference (P < 0.0001) between the mean of P300 latency in depressed and nondepressed control subjects was also found. Mean score of P300 latency in depressed group was significantly high (346.918 ± 19.515) compared to the nondepressed control subjects (303.741 ± 6.378). There was a significant difference in the mean of P300 latency between mild and severe (P < 0.0001), mild and very severe (P < 0.0003), as well as moderate and severe (P < 0.0001) level of depression. Conclusions: P300 latency may be used as an indicator of MDD and it is directly proportional to the severity of MDD.

Keywords: Hamilton depression rating scale, major depression, P300 latency, severity

How to cite this article: Tripathi SM, Mishra N, Tripathi RK, Gurnani K C. P300 latency as an indicator of severity in major depressive disorder. Ind Psychiatry J 2015;24:163-7

How to cite this URL: Tripathi SM, Mishra N, Tripathi RK, Gurnani K C. P300 latency as an indicator of severity in major depressive disorder. Ind Psychiatry J [serial online] 2015 [cited 2016 May 5];24:163-7. Available from: http://www.industrialpsychiatry.org/text.asp?2015/24/2/163/181726

Caregiver burden and quality of life of key caregivers of patients with dementia

Caregiver burden and quality of life of key caregivers of patients with dementia Srivastava G, Tripathi RK, Tiwari SC, Singh B, Tripathi SM - Indian J Psychol Med

Abstract

Background: Dementia is the most devastating cognitive disorder of the elderly and needs extra attention to care. Therefore, this study was conducted to identify the caregiver burden of dementia key caregivers and their Quality of Life (QOL). Materials and Methods: Sample consisted of purposively selected 24 dementia key caregivers fulfilling the inclusion criteria from the in-patient of the Department of Geriatric Mental Health, King George's Medical University, Lucknow, Uttar Pradesh, India. Zarit Burden Interview and World Health Organization QOL-BREF were administered. Mean, standard deviation, t-test, Chi-square with Yate's correction were used to analyze the data. Results: All key caregivers felt mild to moderate level of burden. Gender-wise significant difference was found on burden area of "expectation" (P < 0.05). Mean scores on physical, psychological, social relationship, and environmental QOL were found to be on lower side. A negative correlation was found between burden and QOL. Conclusion: Professional help and supportive psychotherapy can be provided to the key caregivers of dementia patients to reduce their burden, strengthen the coping skill and thus improve their QOL.

A Case Of “Rapidly Progressive” Progressive Supranuclear Palsy

Shailendra Mohan Tripathi, Priti Singh , Ravi Soni, Rakesh Kumar Tripathi , S.C.Tiwari

Progressive supranuclear palsy (PSP) is an uncommon brain disorder that affects movement, control of walking (gait) and balance, speech, swallowing, vision, mood and behavior, and thinking. The disease results from damage to nerve cells in the brain. It is grouped under Parkinson-Plus syndrome as the parkisonian symptoms and cognitive impairment present at the same time........

Tripathi SM, Singh P, Soni R, A case of “rapidly progressive” progressive supranuclear Tripathi RK, Tiwari SC. palsy.  Indian Journal of Psychiatry, 2016; 58(supplement), S146-S147.
available at:
http://www.indianjpsychiatry.org/temp/IndianJPsychiatry585122-1626336_002706.pdf

Personality of Schizophrenics on Dimension Personality Inventory (DPI)

IJSAR, 2(8), 2015; 08-15

International Journal of Sciences & Applied Research
www.ijsar.in

Rupali Chandola1, Aradhna Shukla1, Rakesh Kumar Tripathi2*

1Department of Psychology, Kumaun University Campus, Almora, Uttrakhand, India. 2Department of Geriatric Mental Health, King George‟s Medical University UP, Lucknow, India.

Correspondence Address: *Dr. Rakesh Kumar Tripathi, Assistant Professor cum Clinical Psychologist, Department of Geriatric Mental Health, King George‟s Medical University UP, Lucknow, India. _________________________________________________________________________________Abstract: 

This study examined the personality characteristics of 40 schizophrenic inpatients of Psychiatry department, Susheela Tiwari Forest Medical Collage, Haldwani, Uttrakhand and 40 normal controls (General Health Questionnaire-12 negative) from Awas Vikas Colony, Rudrapur, Uttrakhand, India. Subjects fulfilling inclusion/exclusion criteria and giving written informed consent were included in the study. A comparison of their personality profile on Dimension Personality Inventory (DPI)-B revealed that there was significant difference (p<0.05) in the mean scores on different dimensions of personality between schizophrenic and normal group. Schizophrenics were found to be passive, non-enthusiastic, submissive, suspicious, depressive and emotionally instable however, normal individuals were on opposite dimension of these. Males were found to be assertive of both the groups. Study findings revealed that schizophrenics can be differentiated from normals on the basis of personality characteristics.
Keywords: Dimension Personality Inventory, Personality, Schizophrenia
Introduction
Studying personality of an individual was used to be a very interesting subject not only in ancient era but even today. The ancient Indian model of “personality”, described in the Upanishads consists of the five sheaths. These are ‘Annamaya’, ‘Pranamaya’, ‘Manomaya’ ‘Vijnanamaya’ and ‘Anandamaya’. (Das, 1987.) In Atharv Veda and Bhagwat Gita personality was discussed in the terms of Triguna i.- ‘Sattvik Guna’, ‘Rajasik Guna’ and ‘Tamsik Guna’ of an individual (Srivastava , 2012). There are seven types Sattvik, six kinds of Rajasik and three types of Tamasik, total 16 types of personalities under which persons can be classified (Mukherjee , 2007). A triguna scale has....
Full article pdf is available on www.ijsar.in 

Does Personality of Psychopaths differ from Normal?

http://ijsar.in/Admin/pdf/212.pdf


Rupali Chandola1 , Aradhna Shukla1 , Rakesh Kumar Tripathi2 *

1Department of Psychology, Kumaun University Campus, Almora, Uttrakhand, India 1Department of Psychology, Kumaun University Campus, Almora, Uttrakhand, India 2Assistant Professor cum Clinical Psychologist, Department of Geriatric Mental Health, King George‟s Medical University UP, Lucknow, India. Correspondence Address: *Dr. Rakesh Kumar Tripathi, Assistant Professor cum Clinical Psychologist, Department of Geriatric Mental Health, King George‟s Medical University UP, Lucknow, India-226003.

International Journal of Sciences & Applied Research ( IJSAR), 2(12), 2015; 20-26. _________________________________________________________________________________ Abstract

Background: Personality of an individual determines his behavior towards others. Psychopaths behave differently. Therefore, study was conducted to know that, which personality dimension of psychopaths differ from normal. Methods: Study examined personality dimension of 80 subjects selected purposively. Of them 40 were normal subjects (20 male & 20 female) and 40 psychopaths (20 male & 20 female). GHQ-12 negative subjects from the community formed the normal group. Dimension Personality Inventory (DPI-B) was administered on all the included subjects. Results: Mean scores on DPI-B reveal that normal and psychopath group were significantly (p<0.05) differ on all the six personality dimensions i.e. „activity-passivity‟, „enthusiastic-non enthusiastic‟, „assertive-submissive‟, „suspicious-trusting‟, „depressive-non depressive‟ and „emotional instability-emotional stability‟. Mean scores were found to be significantly higher of psychopaths compared with normal group. Conclusion: Personality of psychopath can be differentiated on „depressive-nondepressive‟ and „suspicious-trusting‟ dimensions on DPI-B. Psychopaths were found to be „depressive‟ and „suspicious‟ in present study. Keywords: GHQ-12, DPI, Personality, Psychopaths

Care Needs of Dementia Key Caregivers

Garima Srivastava, Rakesh Kumar Tripathi*, S.C. Tiwari*,  Bhupinder Singh#

*Department of Geriatric Mental Health, King George's Medical University, UP, Lucknow, India

 Abstract:

Background: Dementia is the most devastating mental health problem of elderly and needs extra attention to care. Therefore, this study was conducted to identify the care needs of dementia key caregivers and their quality of life (QOL).

Methods: Sample consisted of purposively selected 24 dementia key caregivers fulfilling the inclusion and exclusion criteria from the inpatient of the Department of Geriatric Mental Health, KGMU, UP, Lucknow. Semi-structured proforma for sociodemographic details, Zarit Burden Interview and WHOQOL-BREF were administered.

Statistical Analysis: Mean, SD, t test, Chi Square with Yate’s correction were used to analyze the data.

Results:  All key caregivers of dementia patients felt mild to moderate level of burden.  Significant difference was found on burden areas of ‘expectation’ (p<.01) and ‘incompetence’ (p<.05) between males and females key caregivers. Mean scores on physical, psychological, social relationship and environmental QOL were found to be on lower side of dementia key caregivers.

Key Words: Dementia, Key care giver, Burden and QOL
Note: Paper was presented in national Annual Conference of Indian Association for Geriatric Mental Health held at Mysore, 2012.

available on following link: http://www.intarchmed.com/content/7/1/26/abstract

Novel occupational therapy interventions may improve quality of life in older adults with dementia

Prakash Kumar, Sarvada Chandra Tiwari, Ashish Goel, Vishnubathla Sreenivas, Nand Kumar, Rakesh Kumar Tripathi, Vineet Gupta and Aparajit Ballave Dey

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International Archives of Medicine 2014, 7:26  doi:10.1186/1755-7682-7-26

Published: 20 May 2014

Abstract (provisional)

Background

Dementia is a major health problem in advancing age with no definitive treatment. Occupational therapy interventions are recognized strategies in treatment of dementia. Quality of life (QOL) assessment has been reliably used as an objective index of an individual's well being pertaining to interventions in dementia. A randomized controlled trial was conducted to study the effects of a novel occupational therapy program in improving QOL of subjects having mild to moderate dementia.

Methodology: 273 subjects older than 60 years were screened. 196 were excluded having cognitive impairment with no dementia (CIND). Remaining 77 subjects after satisfying DSM IV criteria for diagnosis of dementia were included in the study and were randomly assigned to experimental and control groups. Experimental group received a novel occupational therapy regimen along with medical treatment, while control group received only medical treatment for 5 weeks. Outcome measures included standard occupational therapy assessment and WHOQOL-BREF. Subjects were assessed at baseline and post intervention.

Result: The mean age of participants was 69.39 years with male preponderance (80.5 % male, 19.5%female). The quality of life (QOL) scores of physical and psychological domain in experimental groups significantly increased from 37.30 +/- 5.42 and 45.13 +/- 3.52 to 45.43 +/- 7.32 and 51.50 +/- 6.46 respectively. The QOL scores in social and environmental domains did not change significantly. The QOL scores in control groups declined in all domains with statistical significance found in social and environmental domain. (29.67 +/- 4.58 and 38.49 +/- 1.77 to 28.45 +/- 5.26 and 38.18 +/- 2.15 respectively)

Conclusion

This novel occupational therapy program improved the short term physical performance and psychological well being domain of quality of life in older adults with dementia. An improved physical performance is achieved by physical exercise of novel program and it creates sense of independency, increased motivation, positive outlook and reduced behavioral and psychological symptoms. The long term effects of the intervention can be ascertained in a study with longer period of intervention and follow-up.

Trial registration: [CTRI/2014/01/004290]

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.